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    • 专利摘要:
    PRESSURE DETECTION SYSTEM, CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP AND METHOD FOR MEASURING FLUID PRESSURE IN A DISPOSABLE INTRAVENOUS PACKAGE CONNECTED TO A FLUID SUPPLY PUMP. wherein fluid pressure measurement systems and methods in a disposable intravenous (IV) set connected to a fluid supply pump are disclosed; at least one detection device coupled to the fluid supply pump is provided; A chamber (182) is provided having a movable element (172), such movable element (172) being configured to move in response to changes in fluid pressure within the disposable IV assembly and thereby cause a change in a detected measurement variable associated with the sensing device without making contact with the sensing device; a measurement signal indicative of the detected measurement variable is generated; the fluid pressure within the disposable IV set is determined based on the measurement signal.
    公开号:BR112012022410A2
    申请号:R112012022410-7
    申请日:2011-03-10
    公开日:2021-08-10
    发明作者:Robert D. Butterfield
    申请人:Carefusion 303, Inc；
    IPC主号:
    专利说明:

    . 1/41 "PRESSURE DETECTION SYSTEM, CASSETTE CONFIGURED TO COUPLE TO A PUMP FOR POWER SUPPLY FLUID AND METHOD FOR MEASURING FLUID PRESSURE IN A PACKAGE DISPOSABLE INTRAVENOUS PUMP CONNECTED TO A FLUID SUPPLY PUMP”.
    FIELD OF APPLICATION This patent application refers to a pressure sensor. In particular, this patent application concerns systems and methods for measuring fluid pressure within a disposable intravenous (IV) set connected to a fluid supply pump.
    BACKGROUND Fluid feed pumps are frequently used in medical and other fields. In the medical fields, for example, the use of intravenous (IV) infusion pumps to release fluids such as medications and nutrient solutions has been a widespread practice in hospitals. IV infusion pumps have gained widespread acceptance because they are capable of delivering IV fluids under precise and tightly controlled conditions so that medications and the like can be delivered intravenously to a patient where they deviate from a desired delivery rate. they can have harmful consequences. — An IV infusion pump device is often provided with a pumping mechanism that is adapted to accept a cassette containing a pumping chamber. The cassette is normally designed for one use only, and needs to be economically manufactured to reduce its cost. The cassette is normally activated by a reciprocal (e.g. peristaltic) driving force of the pumping mechanism and has a fluid inlet for connection to a tube leading to the supply container and a fluid outlet for connection to a tube providing the IV fluid to the patient. For control and monitoring purposes, it is desirable to measure the fluid pressure inside the disposable IV cassette. For example, the fluid pressure signal can be used to detect, inter alia, an empty supply bottle, an occluded inlet or outlet path, a bottle-channel association, the level of liquid in the bottle and the resistance to flow of the fluid pathway. It is a challenge to provide a pressure sensing system to measure fluid pressure inside the cassette that is both cost-effective and accurate. Ideally, the precision sensor measures positive and negative pressures, negative pressures commonly arising from the elevation of the patient's [solution] bag relative to the sensor element. High resolution of the order of 1 mmHg is required, as well as for the purposes mentioned above.
    Conventionally, fluid pressure within a cassette is measured by a contact measurement method in which the cassette or an object physically connected to the cassette makes contact with a sensing device (eg, a resistive strain gauge force sensor ) — to exert a pressure/contact force on the sensing device. In such contact-based pressure sensing systems, the sensing device is normally and intentionally pre-loaded with a positive pressure/force such as exerted by a deformed pipe wall, in order to artificially polarize a pressure point. zero so that a negative pressure can be measured. One problem with such a positive bias scheme with a precharged detection device is that the precharge force can decrease over time due to the resulting slack voltage at the point related to bias fluctuating downwards over time. This can cause the actual fluid pressure to be underestimated.
    SUMMARY The applications described here solve the above-discussed problem associated with contact-based pressure measurement by providing systems and methods for the non-contact measurement of fluid pressure within a cassette connected to a fluid supply pump, such as an IV infusion pump. In one aspect, non-contact pressure sensing involves coupling a sensing base having a non-contact sensing device to the pump and coupling a movable element having a variation measurement sensing element to an element in the disposable IV set. The measuring sensing element moves in response to changes in fluid pressure in the fluid path and thus causes a signal change proportional to the output of the sensing device. Fluid pressure is determined from a measurement signal — indicative of the detected measurement variable. — Certain applications provide a pressure sensing system to measure fluid pressure within a disposable IV set connected to a fluid supply pump. The system may comprise a detection base coupled to a pump. The sensing base may have at least one sensing device which is stationary with respect to the sensor base. The detection device can be configured to generate a measurement signal based on a detected measurement variable. The system may further comprise a measuring circuit electrically connected to the detection device. The system may further comprise an element within the disposable IV assembly configured to be positioned in proximity to the base of the sensor. The disposable component may have a fluid inlet and fluid outlet, and a movable element to move with changes in fluid pressure within the cassette. The amount of movement of the moving element can be related to the amount of change in fluid pressure. The system may further comprise a variation measurement sensing element coupled to move with the movable element through a non-contact sensing field, such as those of light or other electromagnetic fields. The variation measurement sensing element can thus cause a change in the detected measurement variable without making contact with the detection device.
    Certain applications provide a cassette configured to couple a fluid feed pump. The cassette may comprise a pumping chamber having a fluid inlet and a fluid outlet and be configured to receive a fluid from a fluid storage unit via the fluid inlet. The cassette may further comprise a diaphragm structure coupled to the pumping chamber, the diaphragm structure comprising a | movable element configured to move in accordance with changes in fluid pressure within the pumping chamber and thereby cause a detected measurement variable to change, detected by at least one sensing device coupled to the fluid supply pump without making contact with the sensing device, the amount of movement of the moving element being related to the amount of change in fluid pressure.
    Certain applications provide a method to measure fluid pressure in a disposable IV set connected to a fluid feed pump.
    The method may comprise at least providing a sensing device coupled to the fluid supply pump.
    The method may further comprise providing a chamber that has a movable element configured to move with the movable element in response to changes in fluid pressure within the disposable IV set and thereby cause a change in a detected measurement variable associated with the sensing device without making contact with the sensing device.
    The method may further comprise generating a measurement signal indicative of the detected measurement variable.
    The method may further comprise determining the fluid pressure within the disposable IV set based on the measurement signal. = Certain applications provide — a pressure sensing system to measure fluid pressure within a disposable IV set connected to a fluid supply pump.
    The system may comprise a detection base coupled to a pump.
    The sensing base may have at least one sensing device which is stationary with respect to the sensor base. The detection device can be configured to generate a measurement signal based on a detected measurement variable. The system may further comprise a measuring circuit electrically connected to the detection device. The system may further comprise an element within the disposable IV set configured to be positioned in proximity to the base of the sensor. The disposable component may have a fluid inlet and fluid outlet, and a movable element to move with changes in fluid pressure within the cassette. The amount of movement of the moving element can be related to the amount of change in fluid pressure. The system may further comprise a variation measurement sensing element coupled to move with the movable element through a non-contact sensing field such as light or other electromagnetic fields. The variation measurement sensing element can thus cause a change in the detected measurement variable without making contact with the detection device.
    Certain applications provide a disposable pressure sensing element configured to attach to a fluid feed pump. The element can be used for pressure sensing only or it can be combined = with other features such as a pumping chamber having — a fluid inlet and a fluid outlet. The sensing element may be configured to receive a fluid from a fluid storage unit via the fluid inlet. The sensing element may further comprise a diaphragm structure.
    The diaphragm structure may comprise a movable member configured to move with changes in fluid pressure in the fluid delivery path.
    The amount of movement of the moving element can be related to the amount of change in fluid pressure.
    The disposable pressure sensing element can further be designed to provide a varying physical quality, such as the position of a non-contact measurement sensing element.
    The variation measurement sensor element can thus cause a change in a variable of the detected measurement, being detectable by at least one detection device coupled to the fluid supply pump without making contact with the detection device.
    Certain applications provide a method of measuring fluid pressure within a disposable pressure sensing element or combined within a multifunctional disposable cassette connected to a fluid feed pump.
    The method may comprise at least providing a sensing device coupled to the fluid supply pump.
    The method may further comprise providing a movable element coupled to the cassette and having a variation measurement sensing element.
    The variation measurement sensing element may be coupled to move with the — moving element, in response to changes in fluid pressure — within the cassette and thereby cause a change of a detected measurement variable associated with the sensing device without doing contact with the detection device.
    The method may further comprise generating a measurement signal indicative of the detected measurement variable. The method may further comprise determining the pressure of the fluid within the cassette based on the measurement signal.
    It is to be understood that both the foregoing summary and the detailed description below are exemplary and explanatory and are intended to provide further explanation regarding the applications as claimed.
    DESCRIPTION OF THE DRAWINGS The accompanying figures, which are included to provide a further understanding of the present patent application and are incorporated in and constitute a part of this specification, illustrate disclosed applications and, together with the description, serve to explain the principles of disclosed applications.
    Figure 1 is a cross-sectional view of an exemplary non-contact pressure sensing system of the capacitive type 100 that relies on capacitance as a variable of the detected measurement under certain applications; Figure 2 is a diagram of the exemplary non-contact pressure sensing system of the capacitive type of Figure 1, shown with the cassette separated from the base of the sensor; = Figure 3 is a bottom-up view of a printed circuit substrate showing the first and second boards formed on the substrate; Figure 4 is a top-down view of a diaphragm structure showing a conductive layer formed along a movable member of the diaphragm structure; Figure 5 is a cross-sectional perspective view of the diaphragm structure and a coupler configured to couple the diaphragm structure to the cassette, in accordance with certain applications; Figure 6 is a cross-sectional view of an exemplary optical-type non-contact pressure detection system that relies on light intensity as the detected measurement variable, in accordance with certain applications; Figure 7 is a cross-sectional view of an exemplary non-contact pressure sensing system of the magnetic type that relies on magnetic field as the detected measurement variable, in accordance with certain applications; Figure 8 is a flowchart illustrating an exemplary process for making a non-contact fluid pressure measurement within a cassette, in accordance with certain applications; and Figure 9 is a block diagram illustrating an exemplary computer system upon which certain features of the systems and methods described herein can be implemented. —
    DETAILED DESCRIPTION In the following detailed description, several specific details are set forth to provide a complete understanding of the described and claimed applications. It will be evident, however, to a person skilled in the art that applications can be practiced without some of these specific details. In other examples, well-known structures and techniques have not been shown in detail, to avoid the present patent application being unnecessarily ambiguous.
    The word “exemplary” is used here to mean “to serve as an example, illustration or instance”. Any application or design described herein as “exemplary” is not necessarily to be construed as preferable or advantageous over other applications or designs.
    Several applications of the present patent application address and solve the problems associated with conventional systems and methods of measuring fluid pressure within a cassette that rely on a positive bias in order to also measure at positive fluid pressures and negative. Certain applications of the present patent application provide a non-contact pressure sensing system for measuring fluid pressures within a cassette connected to a fluid supply pump. A sensing base having at least one sensing device is coupled to the pump, and a movable element having a variation measurement sensor element is coupled to the cassette. — The variation measuring element moves with changes in the — pressure of the fluid within the cassette, and thus causes a change in a detected measurement variable (such as capacitance, light intensity, and magnetic field) without make contact with the detection device. The element of Petition 870210052505, of 06/11/2021, p. 14/87 Mm pressure sensing can be configured within a sterile multifunctional disposable 'cassette' or within a single-purpose housing exclusively used for pressure measurement. i Figure 1 is a cross-section of an exemplary non-contact pressure sensing system of the capacitive type 100 that relies on capacitance as a variable of the detected measurement under certain applications.
    System 100 includes a detection base 101A coupled to a pump body 110 and a cassette 102A.
    Cassette 102A is configured to couple or charge the pump, or, more particularly, the detection base 101A.
    Conventional bonding structure can be applied to bond cassette 102A to detection base 101A, such as a snap-in coupling.
    Figure 1 shows detection base 101A and cassette 102A in a connected or loaded state, and FIG. 2 shows detection base 101A and cassette 102A in a detached or unloaded state with an arrow 201 indicating charging or attachment of cassette 102A to detection base 101A.
    In the illustrated example, the sensor sensing base 101A includes a spring loaded structure 130 and a printed circuit (PC) substrate 140. The spring loaded structure 130 is connected to the pump body 110 by means of springs 120 and holds the PC substrate 140 stationary with respect to the rest of the detection base 101A. —. Substrate PC 140 has a first plate 103A and a second plate 104A formed (e.g., deposited and shaped) on an underside of substrate PC 140 facing cassette 102A, and a measurement circuit 105A disposed on the upper side of the PC substrate
    140. The first and second plates 103A, 104A constitute detection elements or devices of the capacitive type non-contact pressure sensing system 100. The figure. 3 is a bottom-up view (e.g., in the z+ direction) of the PC substrate 140 showing the first and second board 103A, 104A. In the illustrated example, the first and second plate 103A, 104A are two semicircular shaped plates separated by a small insulating aperture 310 (e.g., 0.005 inches). Alternatively, one or both of the first and second plates 103A, 104A may have different shapes, including, but not limited to, rectangles, triangles, complete circles, and a circle and "a ring around the circumference. Returning to the figure". 1, the first and second boards 103A, 104A are electrically connected to a measurement circuit 105A via the sheathed conductor through holes 142 provided in the substrate PC 140. In certain applications, the measurement circuit 105A includes a sensor [Integrated circuit] measuring devices such as an Analog Devices i AD7754 [Analog Devices] and the like, with the capability of measuring differential capacitances. Alternatively, the measuring circuit 105A may comprise a plurality of discrete digital components and/or analogs == which provide a signal excitation and signal conditioning functions, for example. In the illustrated example, the detection base 101A further includes a thin insulating layer 160 comprising an insulating material, such as Mylar or Parylene, to cover the first and second plate 103A, 104A so as to provide protection from electrostatic discharge damage to the measurement circuit 105A and other electronic components. Cassette 102A includes a cassette body 180 and a diaphragm structure 170 coupled to cassette body 180. Cassette body 180 includes a pumping chamber 182 and a wall 182 for the pumping chamber
    182. Although not shown in the portion shown in FIG. 1, cassette body 180 further includes a fluid inlet that leads to a supply container for receiving fluid into pumping chamber 182, and a fluid outlet that leads fluid out to a receiving device or portion (by example, a patient). The diaphragm structure 170 includes a movable element 172, a deformable element 176, and a sidewall 178. In the illustrated example, the movable element 172 is a flat disc. Movable element 172 is coupled to sidewall 178 by means of deformable element 176 coupled to the perimeter of movable element 172 on one side and to an interior perimeter of sidewall 178 on the other side. Diaphragm structure 170 also includes a cavity 179 that is configured to receive fluid from cassette body 180 (e.g., pumping chamber 182). = Cassette 102 further includes a —— conductive layer 109A formed on (e.g., deposited or coated onto, affixed or glued to) disc 172. Figure 4 is a top-down view (e.g., in the z-direction. ) of diaphragm structure 170 which exhibits a conductive layer 109A formed over movable member 172 of the diaphragm structure. As will be discussed further below, the conductive layer 109A constitutes a variation measurement sensor element of the capacitive type non-contact detection system 100. As used herein, the term "variation measurement sensor element" refers to a structure , a device, layer, or component that can be coupled to a movable element (such as disk 172) to move relative to one or more detection devices (e.g., first and second plate 103A, 104A) in response to changes in fluid pressure within the cassette and thus causing a corresponding change in a detected measurement variable (such as capacitance between the first and second plates 103A, 103B). Examples of other variation measurement sensing elements include an optical attenuator employed in an optical-type non-contact pressure sensing system (figure 6), and a magnet for use in a magnetic-type non-contact pressure sensing system ( FIG. 7). The illustrated applications are exemplary only, as other types of non-contact pressure sensing systems may be used.
    Fig. 5 is a cross-sectional perspective view of diaphragm frame 170 and a coupler 500 for coupling the diaphragm frame to cassette body 180 (Fig. 1) in accordance with certain applications. — In certain applications, coupling comprises placing the sensing element close to a sensing apparatus inside the pump. For clarity, diaphragm structure 170 is shown without a variation-measuring sensing element (e.g., conductive layer 109A) disposed over movable element 172. Deformable element 176 is connected between the outer circumference of movable element 172 and the inner circumference of sidewall 178. Deformable element 176 is configured to deform in response to changes in fluid pressure within cassette 102A, or more specifically within pumping chamber 182 of cassette body 180, and so do cause the movable element 172 to move in the z+ direction if the pressure is increasing or in the z- direction if the pressure is decreasing.
    In the illustrated example, the cross section of the deformable element 176 has an “S” or “sigmoid” shape, but the cross section can have another shape, such as a thin rectangle, a curvilinear shape, a “Z” shape or a shape. in “U”. In certain applications, the movable element 172 is not flexible, meaning that the movable element does not flex or deform when subjected to a non-zero fluid pressure.
    In these applications, only the deformable elements 176 flex or deform when subjected to a non-zero fluid pressure.
    The movable element 172 and the deformable element 176 can be made to have different flexibility or deformability (for example, the former non-flexible and the latter flexible), by making them, for example, with different materials, of different thicknesses, and/ or n= different transversal formats.
    In one aspect, using a non-flexible movable element is advantageous because there is less net volume change during pressure measurement.
    In other words, by getting the non-flexible and movable rigid member, it helps to minimize the compliance value, for example,
    up to about 0.1 pL/mmHg.
    Low compliance for a pressure sensor means that the act of measuring pressure has little effect on the measurement state, ie on the fluid pressure as well as the fluid displacement itself.
    Furthermore, the non-flexible movable element may better preserve the structural integrity of the variation measurement sensor element such as the conductive layer 109A connected to the movable member.
    For example, a conductive layer that is coated onto a movable flexing member can be peeled off or peeled away from the movable member after repeated flexing of the movable member.
    Furthermore, the use of the non-flexible movable element in the applications of the present patent application may also result in a more controlled, linear, and repeatable sensitivity (displacement change per unit of pressure variation). In other applications, both the deformable element 176 and the movable element 172 are made to flex or deform when subjected to a non-zero fluid pressure.
    In still other applications, a movable flexible/deformable element is connected directly to the sidewall 178, without having a deformable element in between.
    Furthermore, in the illustrated example, the movable element 172, the deformable element 176, and the sidewall 178 are formed of the same material, such as a polycarbonate, in a single mold.
    Alternatively, the movable element 172, the deformable element 176, and the sidewall 178 are made of two or more different materials and are molded together.
    In some such applications, the movable element 172 and sidewall 178 are made of a polycarbonate material, while the deformable element is made of a thermoplastic elastomer for flexibility.
    In still other applications, movable disk 172 is made of a metal and functions like conductive layer 109A, thus eliminating the need for a separate conductive layer.
    Referring now to Figure 5, coupler 500 is configured to couple or connect to diaphragm structure 170 to cassette body 180, or more specifically to pumping chamber 182, both fluidly and mechanically.
    In the illustrated example, coupler 500 includes a first outer wall 501 and a second outer wall 502. The first outer wall 501 is used to form a sealed mechanical coupling (e.g., a snap fit) between the coupler 500 and the housing frame. diaphragm 170. The second outer wall 502 is used to form a sealed mechanical coupling between the composite diaphragm engagement frame and the cassette body 180 (Figure 1). In the illustrated application, second outer wall 502 is inserted (e.g., pressure-adjusted) into an opening formed in wall 184 of pumping chamber 182 (FIG. 1). Coupler 500 also includes openings 510 for establishing a connection between fluid cavity 179 and pumping chamber 182 to equalize fluid pressure therebetween. — In operation, cassette 102A is — loaded or connected to sensing base 101A, as indicated by arrow 201 of Figure 2. When cassette 102A is initially coupled to sensing base 101A, springs 120 are compressed and exert a force of restore (eg in z-direction)
    against cassette 102A via frame structure 130. This spring loaded device avoids most of the mechanical tolerance stacking errors and noise created by relative movement between detection base 101A and cassette 102A.
    At this stage, there is no net pressure within the cavity 109, and there is no net force exerted on the movable element 172. The movable element 172 is therefore at its quiescent point of zero pressure.
    After cassette 102A is coupled to base 110A and a fluid (medical liquid, for example) is introduced into pumping chamber 182 of cassette 102, cavity 179 receives a portion of the fluid through apertures 510 in coupler 500 (Fig. 5 ). The fluid pressure within the cavity 179 is thus made to be substantially the same as the fluid pressure within the pumping chamber 182 (with a small possible DC displacement). Fluid pressure (positive or negative) within cavity 179 exerts force (positive or negative) on movable element 172 and causes movable element 172 to move.
    For example, if the pressure is positive, the movable element 172 moves in the z+ direction from the quiescent point of zero pressure to the first and second plate 103A, 104A.
    On the other hand, if the pressure is negative, the movable element 172 moves in the z- direction from the quiescent point of zero pressure away from the = first and second plate 103A, 104A.
    The positive pressure therefore causes the conductive layer 109A, which is coupled to the movable element 172, to approach the first and second plates 103A, 104A and result in an increase in capacitance between the two plates 103A, 104A.
    On the other hand, the negative pressure causes the conductive layer 109A to move away from the first and second plates 103A, 104A and results in a decrease in capacitance between the two plates 103A, 104A.
    The measurement circuit 105A is configured to measure capacitance between the first and second plates 103A, 104A and provide a measurement signal indicative of the capacitance.
    This can be accomplished by one of many known capacitance measurement methods, including differential capacitance measurement involving one or more fixed reference capacitors.
    Integrated circuits (ICs), which are designed for such differential capacitance measurements, are commercially available, an example being Analog Devices AD7754. Some of these specific IC applications can emit digital data indicative of the measured capacitance.
    Alternatively, an IC or a combination of discrete analog/digital elements designed for capacitance measurement can output an analog measurement signal which can then be converted to digital data for use by a processor by an analog-to-digital converter.
    A processor can then receive digital data indicative of capacitance and determine the fluid pressure inside the cassette from a known relationship between the two quantities - an equation or a lookup table = that may account for a non-linearity in the — capacitance versus fluid pressure response.
    The equation and lookup table can also contribute any pre-set DC pressure displacement between the fluid pressure inside pumping chamber 182 and the fluid pressure inside cavity 179. The result is an accurate non-contact measurement. and repetitive positive and negative fluid pressures within the cassette (e.g., pumping chamber 182) without pre-loading the sensing device and related bias of a zero pressure point.
    Although the above discussion has focused on capacitance as the detected measurement variable, it should be appreciated by those skilled in the art in view of the present description that various alternative applications can be applied without departing from the scope of the present description.
    For example, Figure 6 is a cross-sectional view of an exemplary non-contact pressure detection system of the optical type 600 that relies on light intensity as the detected measurement variable under certain applications.
    The optical type 600 non-contact pressure sensing system illustrated in FIG. 6 shares many structural elements with the capacitive-type non-contact pressure sensing system 100 illustrated in Figure 1, and descriptions of shared elements will not be repeated.
    Instead, the following description focuses on comparing and contrasting the two pressure sensing systems.
    In the illustrated example of figure 6, = the optical type non-contact pressure detection system 600 — applies a light source 103B and a light detector 104B as detection devices, and an optical attenuator 109B as the detection element for measuring pressure. variation.
    The 103B light source may be a laser or a non-laser light source such as Petition 870210052505, dated 06/11/2021, p. 24/87 It is an LED.
    Light detector 104B may include one or more photosensitive elements, such as photodiodes or photoresistors, which are capable of providing an indication of a received light intensity in the form of a change in current or resistance, for example.
    In the illustrated example, the light detector 104B includes a vertical array of photosensitive elements 610 for the purpose of providing a noise-average integrator of the received light intensities.
    However, in alternative applications, the light detector 104B contains only one photosensitive element, and noise is averaged through repeated measurements.
    As with conductive layer 109A in capacitive-type non-contact pressure sensing system 100, optical attenuator 109B is coupled to (e.g., connected to, connected over, fixed to, integrated with) moving element 172 so that optical attenuator 109B moves in conjunction with movable member 172 as the fluid pressure within cassette 102B changes.
    Optical attenuator 109B can comprise an optically absorptive material (e.g., a structural plastic such as polycarbonate, isoplast, acrylic, and the like that can be made opaque with the addition of dyes), which have relatively absorbent values. high.
    In operation, optical attenuator — 109B receives incident light beams 602 emitted by light source — 103B and transmits attenuated light beams 604. Depending on the relative positions of the sensing devices and optical attenuator 109B, at certain pressures, an upper portion of the incident light beams 602 cannot even pass through the optical attenuator 109B. The attenuated light beams 604 (and possibly an unattenuated portion of the incident light beams 602) are received by the vertical array of photosensitive elements 610 and provide measurement signals. A measurement circuit 105B receives measurement signals from individual photosensitive elements and sums the measurement signals, whether in the analog domain or in the digital domain. Alternatively, the sum of the measurement signals (e.g., photocurrents) is physically carried out within the light detector 104B to produce a summed measurement signal, and the measurement circuit 105B receives and processes the summed measurement signal. Regardless of the choice of mechanism, the sum of the measurement signals from the multiple photosensitive elements 610 provides an average noise integrator of the received light intensities, each of which may have a significant noise component related to intrinsic thermal noise and noise related to external factors, such as vibration of the 109B optical attenuator, and therefore improve the accuracy and repeatability of fluid pressure measurement.
    In the illustrated example of Figure 6, the thickness of the optical attenuator 109B in the direction of light travel (for example, the thickness of the x-direction) varies along the direction of movement of the movable element 172 (for example, a — z direction) . Therefore, the greater the movement in the — z+ direction of the movable element (corresponding to an increase in fluid pressure within the cassette), the greater the net attenuation of the incident light beams 602 by the optical attenuator 109B and therefore smaller are the light intensities received by the light detector 104B.
    Conversely, the smaller the movement in the z+ direction of the movable element (corresponding to a decrease in fluid pressures within the cassette), the smaller the net attenuations of the incident light beams 602 by the optical attenuator 109B and, therefore, the greater the light intensities received by the light detector 104B.
    Thus, in the particular illustrated arrangement, the measurement of the detected variable - received light intensities - has a negative or inverse relationship to fluid pressures within cassette 102B.
    However, it should be appreciated by those skilled in the art, in light of the present description, that the particular device and the resulting inverse relationship is provided for illustration purposes only, and other arrangements and relationships are possible to be made without departs from the scope of this patent application.
    For example, the optical attenuator 109B may be an inverted trapezoid, with the shorter side connected to the movable element 172, in which case the received light intensities would have a positive direct or linear relationship to the fluid pressure within the cassette. 102B.
    In the illustrated example, the attenuation variation by optical attenuator 109B along the z-direction is obtained by providing an optical attenuator having a = uniform absorbance value throughout which the thickness of the — x-direction varies along the direction. z.
    Alternatively, attenuation variation can be achieved by providing an optical attenuator with a uniform thickness in the x-direction in which the absorbance varies along the z-direction.
    This can be achieved, for example, by varying the composition of the material, impurities, or a coating in the z-direction so that the optical attenuator is changed from transparent at one end to opaque at the other end.
    It should be further appreciated by those skilled in the art, in view of the present patent application, that the particular detection device applied, i.e., light source 103B and light detector 104B aligned along the x-direction for emitting and receiving light via the optical attenuator 109B, is one of many modes that optically measure the relative motion of the movable element 172, and other devices can be applied without departing from the scope of the present description.
    For example, in an alternative optical type non-contact pressure sensing system, the pressure sensor is based on the amount of light reflected from a reflective surface coupled to the moving element 172. In this system, the light source can emit the beams of light incident at an angle of incidence (eg -30°) and the light detector receives the reflected light beams traveling at a reflected angle (eg +30°). Depending on the relative positions of the light detector and the reflecting surface, the amount of light received by the light detector varies with the maximum amount that occurs — within the maximum range of the detection system, for example.
    This variation can be correlated with the pressure of the fluid inside the cassette.
    In many optical applications, the light control element (eg, a light attenuator or a reflecting surface) is coupled to a movable element that is part of a disposable cassette.
    Figure 7 is a cross-section of an exemplary non-contact pressure sensing system of the magnetic type 700 that relies on magnetic field as the detected measurement variable, in accordance with certain applications. As with the optical type 600 non-contact pressure sensing system of FIG. 6, the illustrated magnetic-type non-contact pressure sensing system 700 shares many structural elements with the capacitive-type non-contact pressure sensing system 100 illustrated in Fig. 1, and descriptions of the shared elements will not be repeated.
    In the illustrated example of Figure 7, the exemplary magnetic-type non-contact pressure sensing system 70 [sic] applies a magnetic field sensor 104C as the sensing device, and a magnet 109C as the variation measurement sensing element. The magnetic field sensor 10C can be any device that is capable of providing an indication of a magnetic field, non-limiting examples which include a Hall effect sensor, a magnetoresistance (MR) sensor (eg a GMR sensor), and a FluxGate magnetometer. The 109C magnet can be any permanent magnet comprising any magnetizable materials, including, but not limited to, iron, nickel, cobalt, some = rare earth metals, and some of their alloys (eg — Alnico). Magnetic field sensor 104C (eg a Hall effect sensor) is disposed on substrate PC 140 and positioned directly above magnet 109C to mainly measure the z component of the magnetic field generated by the magnet.
    109C.
    In operation, a magnetic field 702 emanates from magnets 109C and fills the surrounding region, as shown in Figure 7. Magnetic field sensor 104C detects a local magnetic field 704 and provides a measurement signal indicative of the location of the magnetic field. 704. The measurement signal is measured and processed by a 105C measurement circuit also provided on the PC 140 substrate. In certain applications, the magnetic detection function of the 104C magnetic field sensor and the measurement/processing function of the measurement circuit 105C are combined into a single magnetic sensor/measurement IC.
    The strength of the z component of the magnetic field 702 of a magnetic bar (magnet) along the axis falls inversely with the square of the magnet's distance.
    Therefore, the z component of the local magnetic field 704 detected by the magnetic field sensor 104C varies according to the movement of the movable element 172. The greater the movement in the z+ direction of the movable element 172 (corresponding to an increase in fluid pressure inside the cassette), the smaller the distance between the magnet 109C and the magnetic field sensors 104C, and therefore the greater the strength of the z- component of the local magnetic field 704 detected by the magnetic field sensor — 104C.
    Conversely, the smaller the movement in the z+ direction — of the movable element 172 (corresponding to a decrease in fluid pressure within the cassette), the greater the distance between magnet 109C and magnetic field sensor 104C and therefore the smaller is the strength of the z component of the local magnetic field 704 detected by magnetic field sensors 104C. Therefore, with the particular illustrated arrangement, the detected measurement variable - local magnetic field strength 104C - has a direct and positive relationship to fluid pressures within cassette 102B. However, it should be appreciated by those professionals with experience in the art, in view of the present description, that several other devices and relationships are possible to be performed without departing from the scope of this description. For example, in alternative applications, magnetic bar 109C may be disposed horizontally (e.g., having its axis along the x-direction) on movable member 172 rather than being disposed vertically, as shown. In such alternative applications, magnetic field sensors 104C can be configured to measure the strength of the x component of local magnetic field 704. Figure 8 is a flowchart illustrating an exemplary process for performing a non-contact fluid pressure measurement within a cassette according to certain applications. Process 800 starts in a state 810, in which one or more detection applications coupled to the pump are provided. Among the examples of one or more detection applications discussed above are the first and second plates 103A, 104A (Figure 1), the light source and light detector 103B, 104B (FIG. = 6), and the magnetic field sensor 104C (figure 7). Such sensing devices are affixed to the interior of frame member 130 and held stationary with respect to sensing base 101A, B, C and pump body 110 during pump operation. The bomb can be any bomb of Petition 870210052505, from 11/06/2021, p. 31/87
    Fluid supply configured to accept cassettes, including IV infusion pumps to deliver medications and liquid nutrients to patients.
    Process 800 proceeds to a state 820 in which a movable element coupled to a cassette is provided.
    Cassettes can be permanent, semi-permanent or disposable.
    In certain applications, the cassette is a disposable IV cassette.
    The movable element is configured to move towards or away from the sensing device (eg in z+/- directions, see figures 1, 6 and 7), depending on whether the fluid pressure is to increase or decrease.
    The movable element is also configured to move away from the sensing device from its quiescent zero pressure point.
    In some applications, the movable element is a non-flexible disk that does not flex or deform when subjected to non-zero fluid pressure.
    The disc may be part of a diaphragm structure, which also includes a deformable portion attached to the disc at its perimeter.
    An example of such a diaphragm structure is described in detail above, with reference to Figure 5. A variation measurement sensing element is coupled to move with the movable element in response to changes in fluid pressure within the cassette.
    The particular choice of variation measurement sensing element depends on the choice of the detected measurement variable. — Examples of the variation measurement sensor element — are (measurement variable detected in parentheses): the conductive layer 109A (capacitance), the optical attenuator 109B (transmitted light intensities), a reflective layer (reflected light intensities) , and the 109C magnet (local magnetic field strength).
    Process 800 proceeds to a state 830, in which a measurement signal indicative of the detected measurement variable is generated by the measurement device(s) and received and processed by a measurement circuit electrically connected to the device(s). (s) detection. Process 800 proceeds to a state 840, in which the pressure of the fluid within the cassette is determined based on the measurement signal. In certain applications, fluid pressure is determined by a processor or computer configured (eg programmed) to receive digital data indicative of the detected measurement variable (eg capacitance, light intensity, magnetic field strength location) either directly from the sensing device(s) or the measuring circuit or from an analog-to-digital converter that receives an analog measuring signal. The processor can determine the fluid pressure within the cassette through the use of an equation or lookup table that accounts for a non-linearity in the detected measurement variable versus the fluid pressure response. The equation and lookup table can also contribute to any DC variation between the fluid pressure in the pumping chamber and the fluid pressure in the cavity. In certain applications, certain aspects of fluid pressure measurements within the cassette described herein are performed by a computer system 900 in response to a processor 904 that executes one or more sequences of one or more instructions contained in the memory
    906. For example, processor 904 can determine fluid pressure within the cassette from digital data indicative of the detected measurement variable by executing instructions involving an equation or a search table that is responsible for a non-linearity in the detected measurement variable versus the fluid pressure response.
    Processor 904 may be a microprocessor, a microcontroller, and a digital signal processor (DSP) capable of executing computer instructions.
    Such instructions can be read into memory 906 from other machine-readable medium, such as data storage device 910. Executing the instruction sequences contained in main memory 906 causes processor 904 to perform the process steps described herein. document.
    One or more processors in a multiprocessing device may also be applied to execute the instruction sequences contained in memory 906. In alternative applications, a physical circuit may be used in place of, or in combination with, software instructions to implement various applications.
    Thus, applications are not limited to any specific combination of hardware and software circuits.
    The term "machine-readable medium" as used herein refers to any medium that — participates in providing instructions to the 904 processor for executing or storing results or parameters (such as variables or constants) to computations such as for the determination of fluid pressure Petition 870210052505, dated 06/11/2021, p. 34/87 ROASTED GIVEN mm inside the cassette based on a detected measurement variable. Such medium can take many forms, including, but not limited to, non-volatile media, volatile media, and transmission media. Non-volatile media include, for example, optical or magnetic disks such as data storage device 910. Volatile media include dynamic memory, such as memory 906. Transmission media include coaxial cables, copper wire and fiber optical, including the wires making up the bus 902. The transmission media may also take the form of acoustic or light waves, such as those generated during radio frequency and those of infrared data communications. Common forms of machine-readable media include, for example, a floppy disk, floppy disk, hard disk, magnetic tape, any other magnetic media, a CD-ROM, DVD, any other optical media, punched cards, a paper tape, any other physical medium with hole patterns, a RAM, a PROM, an EPROM, an EPROM FLASH, any other memory chip or cartridge, a carrier wave, or any other medium from which a computer can take a reading.
    In some applications, after the 904 processor programmatically determines the fluid pressure within the cassette, the pressure values may == be stored on machine readable medium (not shown) or — transmitted to another program or a subroutine that runs on the same processor or a different processor for additional processing. For example, the fluid pressure in the cassette can be used by another program or subroutine to control the flow rate of medication in an IV infusion pump or to detect an occlusion or an empty feeding container.
    The foregoing description is provided to enable any person skilled in the art to practice the various applications described herein. While the foregoing applications have been particularly described with reference to the various figures and applications, it is to be understood that these are for illustrative purposes only and should not be taken as limiting the scope of the present patent application.
    There can be many other ways to implement the present patent application without departing from the scope of the present description. For example, certain applications described here can be implemented as "differential" measurement systems in which there is a second detection channel or elements that "visualize"" only the movement of the fixed portion of the disposable item. Such differential measurement systems allow the subtraction of movement of the disposable item that may be caused by the pumping mechanism from movement associated with target pressure. The optical pressure sensing system described above with respect to FIG. 6 can use an array of photosensors in one — linear packaging. Some of the photosensors can be — arranged to detect the movement of the disposable “frame”.
    Several functions and elements described herein can be separated differently from those shown without departing from the essence and scope of the present patent application. Various modifications to these applications will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other applications. Thus, many changes and modifications can be made with the present patent application, by a professional with experience in the art in question, without departing from the essence and scope of the present patent application.
    A reference to an element in the singular is not intended to mean "one and only one", except where indicated, but rather "one or more". The term “some” refers to one or more. Titles and subtitles underlined and/or in italics are used for convenience only, do not limit the present application, and are not referred to in connection with the interpretation of the description of the present application. All structural and functional equivalents to the elements of the various applications of the present patent application described throughout this patent application, which are known or later will become known to those skilled in the art, are expressly incorporated herein by reference and are intended to be covered by this patent application. Furthermore — further, nothing disclosed herein is intended to be dedicated to — the public irrespective of the fact that such a patent application is explicitly recited in the above description.
    All elements, parts and steps described herein are preferably included. It should be understood that any of these elements, parts and steps can be replaced by other elements, parts and steps or eliminated as will be obvious to professionals with experience in the art. In general, this document discloses fluid pressure measurement systems and methods in a disposable IV set connected to a fluid feed pump. At least one detection device coupled to the fluid supply pump is provided. A chamber is provided which has a movable element, the movable element is configured to move in response to changes in fluid pressure within the disposable IV set and thereby cause a change in a detected measurement variable associated with the sensing device. without making contact with the detection device. A measurement signal indicative of the detected measurement variable is generated. The fluid pressure within the disposable IV set is determined based on the measurement signal.
    CONCEPTS This document has disclosed at least the following concepts: Concept 1. A non-contact pressure sensing system for measuring positive or negative fluid pressures within an insulated fluid passage using a chamber = incorporated within the insulated fluid passage and — connected to a fluid supply pump, the system comprising: a sensing base coupled to a pump, and having at least one sensing device that is stationary with respect to the sensor base, and wherein the detection device is configured to generate a measurement signal indicative of a detected measurement variable; a measurement circuit electrically connected to the detection device to receive the measurement signal; a chamber or bracket configured to couple the sensor base, the chamber including: a fluid inlet and a fluid outlet, and a movable element configured to move with changes in fluid pressure within the chamber and thereby cause a change in measurement variable detected without making contact with the sensing device, the amount of movement of the moving element being related to the amount of change in fluid pressure.
    Concept 2. The system of Concept 1, characterized by the fact that the movable element is not flexible when subjected to a non-zero fluid pressure.
    Concept 3. The Concept 1 system, characterized in that the fluid supply pump is an intravenous (IV) infusion pump. Concept 4. The Concept 1 system, characterized in that the chamber is a housing that is configured to receive an IV fluid to measure the pressure of the IV fluid.
    Concept 5. The Concept 1 system, characterized by the fact that the chamber is a cassette configured to contain a fluid — IV, which is delivered to a patient. — Concept 6. The Concept 5 system, characterized in that the cassette is a disposable IV cassette.
    Concept 7, The system of Concept 1, characterized in that the movable element moves towards the sensing device when the fluid pressure increases, and away from the sensing device when the fluid pressure decreases. Concept 8. The Concept 1 system, characterized by the fact that the movable element is configured to be susceptible to both positive and negative pressures of fluid within the cassette without being pre-charged.
    Concept 9. The Concept 5 system, characterized in that the detection base is connected to the pump by means of at least one spring to cause the detection base to exert a force against the cassette when the cassette is connected to the base . Concept 10. The system of Concept 1 further comprising a variation measurement detection element coupled to the movable element and configured to cause the detected measurement variable to change.
    Concept 11. The Concept 10 system, characterized in that: the detection device comprises a first plate and a second plate coupled to the sensor base; the variation measurement detecting element comprises a conductive layer, and the detected measurement variable comprises a capacitance between the first and second plate.
    Concept 12. The system of Concept 8 further comprising a printed circuit substrate, characterized in that the first and second boards and the measuring circuit are =--disposed on the printed circuit substrate. — Concept 13. The Concept 10 system, characterized by the fact that: the detection device comprising a light source and a light detector coupled to the sensor base; the variation measurement detection element comprising an optical attenuator; and the variable of the detected measurement which comprises an intensity of light received at the light detector.
    Concept 14, The Concept 13 system, the optical attenuator having a thickness in one direction of light travel, characterized by the fact that the thickness varies along one direction of motion of the optical attenuator.
    Concept 15. The Concept 10 system, characterized in that: the detection device comprises a magnetic field sensor coupled to the sensor base; the variation measuring detecting element comprises a magnet, and the detected measuring variable comprises a strength of a magnetic field on the magnetic field sensor.
    Concept 16. The Concept 15 system, characterized in that the magnetic field sensor is a Hall-effect sensor, a magnetoresistive sensor, or a fluxgate magnetometer.
    Concept 17. A cassette configured to couple to a fluid supply pump, the cassette comprising: a pumping chamber having a fluid inlet and a fluid outlet and configured to receive a fluid from a fluid storage unit. fluid through the fluid inlet, and a diaphragm structure coupled to the pumping chamber, the diaphragm structure comprising a movable element > configured to move with changes in fluid pressure — within the pumping chamber and thereby cause a change of a detected measurement variable detected by at least one sensing device coupled to the fluid supply pump without making contact with the sensing device, the amount of movement of the moving element being related to the amount of change in the fluid pressure.
    Concept 18. The cassette of Concept 17, the diaphragm structure comprising a deformable element connected to the perimeter of the movable element and configured to deform in response to changes in fluid pressure within the pumping chamber.
    Concept 19. The cassette of Concept 18, characterized in that the deformable element has a sigmoid-shaped cross section.
    Concept 20. The cassette of Concept 18, characterized in that the movable element is not flexible when subjected to a non-zero fluid pressure.
    Concept 21. The cassette of Concept 18, characterized in that the movable element and the deformable element comprise the same material and are formed in a single mold.
    Concept 22. The Concept 21 cassette, characterized by the fact that the same material includes a polycarbonate.
    Concept 23. The cassette of Concept 18, characterized in that the movable element and the deformable element comprise different materials and are molded together.
    Concept 24. The cassette of Concept 23, characterized by the fact that the deformable element comprises an elastomer — thermoplastic. — Concept 25. The cassette of Concept 18, characterized in that the diaphragm structure comprises a cavity disposed between the pumping chamber and the movable element, the cavity being in fluid communication with the fluid inside the pumping chamber.
    Concept 26. The cassette of Concept 17 further comprising a variation measurement sensor element coupled to the moving element, characterized in that the variation measurement sensor element comprises a conductive layer, and the detected measurement variable comprises a capacitance between two plates.
    Concept 27. The cassette of Concept 17 further comprising a variation measurement sensor element coupled to the moving element, characterized in that the variation measurement sensor element comprises an optical attenuator, and the detected measurement variable comprises an intensity of light measured by a light detector.
    Concept 28. The cassette of Concept 17 further comprising a variation measurement sensing element, characterized in that the variation measurement sensing element comprises a magnet, and the detected measurement variable comprises a strength of a magnetic field measured by a magnetic field sensor.
    Concept 29, A method of measuring fluid pressure in a disposable IV set connected to a fluid supply pump, the method comprising: providing at least one sensing device coupled to the fluid supply pump; providing a chamber having a movable element configured to move with the movable element in response to changes in fluid pressure within the disposable IV set and thereby causing a change in a detected measurement variable associated with the detection device without making contact with the detection device; the generation of a
    ] 40/41 measurement signal indicative of the detected measurement variable; and determining the fluid pressure within the disposable IV set based on the measurement signal.
    Concept 30. The method of Concept 29 which further comprises measuring a negative pressure within the disposable IV assembly without having the bias detection device positively.
    Concept 31. The method of Concept 29 further comprising providing a variation measurement sensing element coupled to the movable element.
    Concept 32. The method of Concept 31, characterized in that: the detection device comprises a first and a second plate; the variation measurement detection element comprises a conductive layer; and the detected measurement variable comprises a capacitance between the first and second plate.
    Concept 33. The method of Concept 31, characterized in that: the detection device comprising a light source and a light detector; the variation measurement detection element comprising an optical attenuator; and the variable of the detected measurement which comprises an intensity of light received at the light detector.
    Concept 34. The method of Concept 31, characterized by the fact > that: the detection device comprises a field sensor — magnetic; the variation measurement detecting element comprises a magnet, and the detected measurement variable comprises a force of a magnetic field to the magnetic field sensor.
    Figure Legends
    Figure 2 T1) LOAD CASSETTE Figure 8 810) PROVIDE A DETECTION DEVICE COUPLED TO THE PUMP 820) PROVIDE A MOBILE ELEMENT COUPLED TO THE CASSETTE AND HAVING
    A VARIATION MEASUREMENT SENSOR ELEMENT 830) GENERATE A MEASUREMENT SIGNAL INDICATIVE OF A VARIATION OF
    MEASUREMENT DETECTED 840) DETERMINE THE FLUID PRESSURE INSIDE THE CASSETTE WITH BASE
    NO MEASUREMENT SIGNAL Figure 9 904) Processor 910) Data storage T2) Module 1/O 906) Memory — |
    权利要求:
    Claims (1)
    [1]
    CLAIMS L, "PRESSURE DETECTION SYSTEM", non-contact to measure positive or negative fluid pressures within an insulated fluid passage using a chamber (182) incorporated within the insulated fluid passage and connected to a supply pump of fluid, the system being characterized in that it comprises: a detection base (101A) coupled to a pump, and having at least one detection device that is stationary in relation to the sensor base, and the device being detection is configured to generate a measurement signal indicative of a detected measurement variable; a measurement circuit electrically connected to the detection device to receive the measurement signal; a chamber (182) or bracket configured to engage the sensor base, the chamber (182) including: a fluid inlet and a fluid outlet, and a movable member (172) configured to move with changes in pressure. of the fluid within the chamber (182) and thus causing a change in the detected measurement variable without making contact with the sensing device, the amount of movement of the moving element (172) being related to the amount of change in fluid pressure . 2 "PRESSURE DETECTION SYSTEM", according to claim 1, characterized by the fact that the movable element (172) is not flexible when subjected to a fluid pressure other than zero.
    SS» "PRESSURE DETECTION SYSTEM", according to claim 1, characterized in that the fluid supply pump is an intravenous (IV) infusion pump.
    4. "PRESSURE DETECTION SYSTEM" according to claim 1, characterized in that the chamber (182) is a housing that is configured to receive an IV fluid to measure the pressure of the IV fluid.
    5. "PRESSURE DETECTION SYSTEM" according to claim 1, characterized in that the chamber (182) is a cassette configured to contain an IV fluid, which is delivered to a patient.
    6. "PRESSURE DETECTION SYSTEM", according to claim 5, characterized in that the cassette is a disposable IV cassette.
    Te "PRESSURE DETECTION SYSTEM", according to claim 1, characterized in that the movable element (172) moves in the direction of the sensing device when the fluid pressure increases and away from the sensing device when fluid pressure decreases.
    8. "PRESSURE DETECTION SYSTEM" according to claim 1, characterized in that the movable element (172) is configured to be sensitive to both positive and negative pressures of fluid inside the cassette without being pre- loaded. >
    9. "PRESSURE DETECTION SYSTEM", according to claim 5, characterized in that the detection base (101A) is connected to the pump by means of at least one spring (120) to make the base detection sensor (101A) exerts a force against the cassette when the cassette is connected to the base.
    10: "PRESSURE DETECTION SYSTEM", according to claim 1, characterized in that it further comprises a variation measurement detection element coupled to the mobile element (172) and configured to cause the change in the detected measurement variable.
    11. "PRESSURE DETECTION SYSTEM", according to claim 10, characterized in that: the detection device comprises a first plate (103A) and a second plate (104A) coupled to the sensor base; the variation measurement detection element comprises a conductive layer (109A), and the detected measurement variable comprises a capacitance between the first (103A) and second plate (104A).
    2. "PRESSURE DETECTION SYSTEM", according to claim 8, which further comprises a printed circuit substrate (140), characterized in that the first (103A) and second board (104A) and the measuring circuit are arranged on the printed circuit substrate (140).
    13. "PRESSURE DETECTION SYSTEM", according to claim 10, characterized in that: the detection device comprising a source = of light and a light detector coupled to the base of the sensor; the variation measurement detection element — comprising an optical attenuator (109B); and the variable of the detected measurement which comprises an intensity of light received at the light detector.
    14. "DETECTION SYSTEM OF
    PRESSURE", according to claim 13, wherein the optical attenuator (109B) has a thickness in the direction of light travel, characterized in that the thickness varies along a direction of movement of the optical attenuator (109B). '
    15. "PRESSURE DETECTION SYSTEM", according to claim 10, characterized in that: the detection device comprises a magnetic field sensor (104C) coupled to the sensor base; the variation measurement detecting element comprises a magnet (1090), and the detected measurement variable comprises a force of a magnetic field (702) on the magnetic field sensor (104C).
    16. "PRESSURE DETECTION SYSTEM", according to claim 15, characterized in that the magnetic field sensor (104C) is a Hall effect sensor, a magnetoresistive sensor, or a magnetometer with fluxgate.
    17. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", characterized in that the cassette comprises: a pumping chamber (182) having a fluid inlet and a fluid outlet and configured to receive a fluid from of a fluid storage unit via the fluid inlet, and a diaphragm structure (170) coupled to pumping chamber nn (182), the diaphragm structure (170) comprising a movable member (172) configured to move with changes in fluid pressure within the pumping chamber (182) and thereby cause a change in a detected measurement variable detected by at least one sensing device coupled to the non-contacting fluid supply pump with the sensing device, the amount of movement of the movable element (172) being related to the amount of change in fluid pressure. :
    18. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 17, characterized in that the diaphragm structure (170) comprises a deformable element (176) connected to the perimeter of the movable element (172 ) and configured to deform in response to changes in fluid pressure within the pumping chamber (182).
    19. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 18, characterized in that the deformable element (176) has a sigmoid-shaped cross section.
    20. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 18, characterized in that the movable element (172) is not flexible when subjected to a fluid pressure other than zero. 21 "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 18, characterized in that the mobile element (172) and the deformable element (176) comprise the same material and are formed in a single mold.
    22. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 21, characterized in that the same material includes a polycarbonate.
    23. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 18, characterized in that the movable element (172) and the deformable element (176) comprise different materials and are molded together. 24, "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 23, characterized in that the deformable element (176) comprises a thermoplastic elastomer.
    25. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 18, characterized in that the diaphragm structure (170) comprises a cavity disposed between the pumping chamber (182) and the element movable (172), the cavity being in fluid communication with the fluid within the pumping chamber (182).
    26. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 17, which further comprises a variation measurement sensor element coupled to the mobile element (172), characterized in that the sensor element of variation measurement comprises a conductive layer (109A), and the variable — of the detected measurement which comprises a capacitance between two — plates.
    27. "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 17, which further comprises a variation measurement sensor element coupled to the movable element (172), characterized in that the sensor element of variation measurement comprises an optical attenuator (109B), and the detected measurement variable comprises a light intensity measured by a light detector. 28: "CASSETTE CONFIGURED TO COUPLE TO A FLUID SUPPLY PUMP", according to claim 17, which further comprises a variation measurement sensor element, characterized in that the variation measurement sensor element comprises a magnet ( 1090), and the detected measurement variable comprises a strength of a magnetic field (702) measured by a magnetic field sensor (104C).
    29. "METHOD TO MEASURE THE
    FLUID PRESSURE IN A DISPOSABLE INTRAVENOUS ASSEMBLY CONNECTED TO A FLUID SUPPLY PUMP", characterized in that the method comprises: providing at least one detection device coupled to the fluid supply pump; providing a chamber having a movable element (172) configured to move with the movable element (172) in response to changes in fluid pressure within the disposable IV set and thus cause a change in a measurement variable detected associated with the detection device without making contact with the detection device; generating a = measurement signal indicative of the detected measurement variable; — and determining the fluid pressure within the disposable IV set based on the measurement signal.
    30. "METHOD TO MEASURE THE
    FLUID PRESSURE IN A DISPOSABLE INTRAVENOUS PACKAGE
    CONNECTED TO A FLUID SUPPLY PUMP", according to claim 29, characterized in that it further comprises the measurement of a negative pressure within the disposable IV set without having the positive bias detection device.
    31. "METHOD TO MEASURE THE
    FLUID PRESSURE IN A DISPOSABLE INTRAVENOUS ASSEMBLY CONNECTED TO A FLUID SUPPLY PUMP", according to claim 29, characterized in that it further comprises the provision of a variation measurement sensor element coupled to the mobile element (172).
    32. "METHOD TO MEASURE THE
    FLUID PRESSURE IN A DISPOSABLE INTRAVENOUS ASSEMBLY CONNECTED TO A FLUID SUPPLY PUMP", according to claim 31, characterized in that: the detection device comprises a first (103A) and a second plate (104A); the variation measurement detection element comprises a conductive layer (109A); and the detected measurement variable comprises a capacitance between the first (103A) and second plate (104A).
    33. "METHOD TO MEASURE THE
    FLUID PRESSURE IN A DISPOSABLE INTRAVENOUS ASSEMBLY CONNECTED TO A FLUID SUPPLY PUMP", according to — claim 31, characterized in that: the — detection device comprising a light source and a light detector, being that the jitter measurement detection element comprising an optical attenuator (109B); and the detected measurement variable comprising a light intensity | Petition 870210052505, of 06/11/2021, p. 53/87 | Rem received in the light detector.
    34. "METHOD TO MEASURE THE
    FLUID PRESSURE IN A DISPOSABLE INTRAVENOUS ASSEMBLY CONNECTED TO A FLUID SUPPLY PUMP", according to claim 31, characterized in that: the detection device comprises a magnetic field sensor (104C); the variation measurement detecting element comprises a magnet (109C), and the detected measurement variable comprises a force of a magnetic field (702) to the magnetic field sensor (104C). —
    类似技术:
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    同族专利:
    公开号 | 公开日
    WO2011119348A2|2011-09-29|
    US20110232388A1|2011-09-29|
    KR101659116B1|2016-09-22|
    EP2550518B1|2016-04-27|
    JP2013522646A|2013-06-13|
    CN102803914B|2015-07-15|
    CA2790698C|2017-04-18|
    CN102803914A|2012-11-28|
    MX2012010619A|2013-02-21|
    EP2550518A4|2013-09-04|
    AU2011229865B2|2015-07-16|
    RU2559142C2|2015-08-10|
    KR20130006623A|2013-01-17|
    RU2012139462A|2014-03-20|
    CA2790698A1|2011-09-29|
    EP2550518A2|2013-01-30|
    WO2011119348A3|2011-12-29|
    US8096186B2|2012-01-17|
    ES2578266T3|2016-07-22|
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    法律状态:
    2021-08-03| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2021-08-17| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2021-12-21| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2022-02-22| B16A| Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/03/2011, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |
    优先权:
    申请号 | 申请日 | 专利标题
    US12/731,001|US8096186B2|2010-03-24|2010-03-24|Systems and methods for measuring fluid pressure within a disposable IV set connected to a fluid supply pump|
    US12/731,001|2010-03-24|
    PCT/US2011/027998|WO2011119348A2|2010-03-24|2011-03-10|Pressure sensing system and method|
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